![]() Anisocoria that is NOT caused by a medical problem is called physiologic anisocoria. The amount of anisocoria can be different from day-to-day and can even switch eyes. Up to 30% of people have anisocoria and it is normal for them. Anisocoria can be normal (physiologic), or it can be a sign of a medical problem. The term anisocoria means that the pupils are not the same size at the same time. Normally pupils are in the same size, with both eyes dilating or constricting together. Is it normal to have pupils of different sizes? In the center, the dark spot is a hole in the iris called the pupil. 1: The iris is the colored part of the eye. When in a dark room the pupil usually gets bigger (or dilates) to allow more light to enter the eye. When in a bright room or in sunlight, the pupil usually gets smaller (or constricts). The size of the pupil depends on how much the iris muscle is constricted (tightened). The empty hole in the middle, which allows light to enter the eye, is called the pupil. It is a round muscle, similar in shape to a donut. The colored part of the eye is called the iris. Partial anhidrosis involving only the medial aspect of the forehead ipsilateral side of the nose is associated with a lesion distal to the carotid bulb. Anhidrosis of the entire face is often associated with a lesion at the level of the carotid artery. The pattern of anihidrosis may help identify the lesion.
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